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Solution Chemistry Determinations for: zinc acetate, zinc gluconate, zinc gluconate glycine (ZGG) and zinc gluconate-citrate
Assertions about the availability of zinc ions in commercial products need reevaluation. Only from the computer computations of the presence of zinc species at physiologic pH 7.4 can accurate determinations be made. The sum of all positively charged zinc species (iZn) at pH 7.4 (iZn) is indicated in each entry below.
Please select the solution chemistry determination computation from the selection below:
Access Adobe Acrobat PDF version of Positively Charged Zinc Species by pH
Computer simulations were performed by Dr. Guy Berthon, Directeur de Recherche CNRS, Equipe de Chimie Bioinorganique Médicale, ICMPS - CNRS FR 1744, Université Paul Sabatier, 118 route de Narbonne, 31062 Toulouse, France.
Stability of metals-ligand reactions is briefly discussed here. Stability of metal-ligands is more comprehensively discussed and reviewed in a series of articles in Berthon, Editor Handbook of Metal-Ligand Interactions in Biological Fluids. The stability of zinc gluconate may be found on page 1185 of Chapter 1 of volume 2 of Eby in "Berthon", while original metal-ligand stability material is collected for use by solution chemists using this NIST resource.
See which commercial lozenges use these solution chemistry characteristics here.